delirium detection with an objective medical device



Right now Prolira is looking for an enthousiastic trainee digital media/graphic design/communication
(click for full description on: Digital%20Media%20Communication%20_1.pdf 


Prolira BV, is a high tech research and development SME and spin-off from the University Medical Center Utrecht, the Netherlands.
The company has 2 founders, who together form the management team: 


Rutger van Merkerk, CEO

Rutger van Merkerk, PhD, MSc.  (CEO) has a wealth of experience in the medical device market, working as a business development manager for medical devices in the University Medical Center Utrecht since 2007. He identified and managed many device development projects. He successfully managed to bring two monitoring devices from idea to market; the Evalan SensiStep and the LivAssured Nightwatch. 


Annemarie Willems, MSc. (CCO) has over 20 years of marketing and sales experience in the international medical device market, always involved in realisation of innovative medical devices. With particularly long experience in planning/quoting and realization of concepts into manufactured single use products (Medisize), entrepreneurship and realization of innovative medical devices (Mount Medical).

The DeltaScan technical core team, featuring Murat, Philip, Rutger, Ellis and Annemarie.







Advisory Board

Arjen Slooter is Professor of Intensive Care Neuropsychiatry at University Medical Center Utrecht the Netherlands, chair of the delirium section of the American Society of Critical Care Medicine guideline committee, and president elect of the European Delirium Association.
His research activities focus on delirium and on long-term neuropsychiatric outcome after critical illness or anesthesia and surgery, using both epidemiological and neuroscientific (EEG, MRI) tools. He is a clinical advisor to Prolira without any financial personal interest in the company. Any (future) profits from EEG-based delirium monitoring will be used for scientific research only

Frans Leijten, MD, PhD. (EEG and clinical expertise) is neurologist and clinical neurophysiologist. Working most of his career with EEG based epilepsy diagnosis and epileptic surgery. He is head of the EEG department and the monitoring unit for invasisve EEG recordings at the University Medical Center Utrecht. Dr Leijten has a special interest in innovative medical companies and he contributes with his wealth of knowledge to Prolira's EEG based DeltaScan. 


Boudewijn Bollen is advisor to Prolira. As a former senior board member of  American medical monitoring device companies, he is specialized in European market introduction and market growth for novel medical monitoring parameters and devices. He played a major role in the market succes of a.o:
- Aspect Medical, that developed and introduced the BIS monitor (an EEG based patient monitor to measure the depth of anaesthesia during surgery). Aspect Medical  was sold to Covidien (currently Medtronic) in 2009.
- Nellcor SpO2 sensor (the world's first disposable oxygen saturarion sensor, which nowadays is
part of standard vital signs monitoring in every hospital). 


Clinical Evaluation team

The University Medical Center Utrecht (Prof. Dr. A. Slooter, neurologist-intensivist and his brain at risk team) leads the groundbreaking research on which Prolira's DeltaScan technology is based.
Prolira's technical team consists of international EEG experts from a.o. Canada and the Netherlands.
Prolira's market introduction team first focus is N-European hospitals.
The team is supported by international industry advisors with a wealth
of experience in the hospital vital signs monitoring market. 



The DeltaScan venture gained support from a.o Rabobank, Technology Foundation STW (funding of excellent technical scientific research), the EU (Horizon 2020 program), InnovatieKrediet by, 2 business angels and venture capitalists Holland Venture and Health Innovations (click for press release, sept 2016).